PCV13 And PPSV23
Administration: Does The Order Affect Immune Response?
(6 October 2017): Monthly
Prescribing Reference (NY)
reported that when PCV13 and
PPSV23 were sequentially given 1 year apart, the observed immune responses in
older adults were higher than those of adults given PPSV23 followed by PCV13,
according to Erica Chilson, PharmD, from Pfizer Inc., Collegeville, PA.
"Although this study was not designed to determine the optimal interval
between PCV13 and PPSV23 doses, it nonetheless provides insight into the immune
response when the vaccines are given sequentially in older adults at an
interval of one year later," concluded Dr. Chilson. Findings from this
analysis support the universal recommendation of giving PCV13 first when use of
both pneumococcal vaccines is appropriate
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